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fat burner

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(@jpinz)
Active Member
Joined: 6 years ago
Posts: 6
 

Re: Re: fat burner

Posted by: Syr
DNP

If we are keeping him from clen why would we send him the direction of dnp lol

As macro said, EC and Thermorexin however nothing will work as great as following a good diet and training program


   
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Bilter
(@bilter)
Estimable Member
Joined: 6 years ago
Posts: 167
 
Posted by: jboldman
This is an interesting read to points out that apoptosis occurs almost immediately.

jb

======

Muscle Nerve. 2005 Dec;32(6):767-74. Related Articles, Links

Dose-dependent apoptotic and necrotic myocyte death induced by the beta2-adrenergic receptor agonist, clenbuterol.

Burniston JG, Chester N, Clark WA, Tan LB, Goldspink DF.

Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Webster Street, Liverpool L3 2ET, UK.

We have investigated the dose- and time-dependency of myocyte apoptosis and necrosis induced by the beta2-adrenergic receptor agonist, clenbuterol, with the aim of determining whether myocyte apoptosis and necrosis are two separate processes or a continuum of events. Male Wistar rats were administered subcutaneous injections of clenbuterol, and immunohistochemistry was used to detect myocyte-specific apoptosis and necrosis. Myocyte apoptosis peaked 4 h after, and necrosis 12 h after, clenbuterol administration. In the soleus, peak apoptosis (5.8 +/- 2.0%; P < 0.05) was induced by 10 mug and peak necrosis (7.4 +/- 1.7%; P < 0.05) by 5 mg x kg(-1) clenbuterol. Twelve hours after clenbuterol administration, 73% of damaged myocytes labeled as necrotic, 27% as apoptotic and necrotic, and 0% as purely apoptotic. Administrations of clenbuterol (10 microg x kg(-1)) at 48-h intervals induced cumulative myocyte death over 8 days. These data show that the phenotype of myocyte death is dependent on the magnitude of the insult and the time at which it is investigated. Only very low doses induced apoptosis alone; in most cases apoptotic myocytes lysed and became necrotic and the magnitude of necrosis was greater than that of apoptosis. Thus, it is important to investigate both apoptotic and necrotic myocyte death, contrary to the current trend of only investigating apoptotic cell death.

this is disturbing. wish I had not touched the stuff in the past. My highest dose was 100mcg at a BW of 195lbs. Had the bad sides (shakes, insomnia) but fat loss was no better that cardio & clean diet.


   
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jboldman
(@jboldman)
Member
Joined: 7 years ago
Posts: 1450
 

likewise i wish i had never used it.

jb


   
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