INFO: bro's with joint problems read

i posted about thsis stuf years ago, glad it finally caught on with you guys. i have used it for a couple years and have also used Sodium hydralanaute which i find to be a much better product, partly becasue it lasts longer in the syestem which means less injects. these products are legal, there actaully found in some beauty skin creams as well. the reasosn the never enterted human medicine is because they actaully cure joint problems instead of just masking Pain like NSAIDS which means they would be much less profictable than NSAIDS to teh pahrm industry, but human based products are slowing starting to enter the market and are much more expensive than teh vet products. what you guys are paying 60 bucks for cosst liek 600 for teh human product of sodium hydralanate. i will dig up my post and bump it. Jim

heres the info i posted quite a while back what you guys are using is Polysulfated glycosaminoglycan which is not abad producs but i perosanlly like soduim hydralante better. dosing info is included. if only you guys would have doen w search you would have seen this from before. i used these products for elbow tendinitis while playing baseball, they are great products tahts work awesome info: Polysulfated glycosaminoglycan (PSGAG), is a semi-synthetic pharmaceutical prepared by sulfate esterification of glycosaminoglycan molecules. It is chemically similar to the natural glycosaminoglycan of cartilage tissue, making it more than just an anti- inflammatory medication for joint trauma; it is a medical therapy that not only treats the symptoms but actually treats the underlying processes threatening to turn joint injury into joint degeneration. Administered by intramuscular injection, PSGAG acts to break the degenerative cycle while reducing the symptoms of joint disease: PSGAG inhibits more than a dozen joint-damaging enzymes. Decreases inflammation and pain by inhibiting prostaglandin-E2 synthesis, decreasing the release of toxic-free radicals, and inhibiting the complement cascade. Promotes the production of new hyaluronate in the synovial fluid to help lubricate the joint (doubles the concentration in 48 hours) and facilitate cartilage nutrition, and stimulates chondrocytes to synthesize new cartilage components. In clinical trials, peak therapeutic levels were achieved in the synovial fluid and cartilage of the joint within two hours of intramuscular injection, and levels were 33% higher where PSGAG'S presence was most critical: in inflamed versus normal joints. The efficacy and safety of PSGAG in the treatment of synovitis and degenerative joint disease of the carpus has been well supported in clinical trials and in actual field use: In clinical field trials involving 39 horses with naturally-occuring traumatic or degenerative joint disease, investigators rated the response good-to-excellent in 90% of the horses treated with intra-articular PSGAG and 88% in horses treated intramuscularly. PSGAG has been proven safe. Subacute toxicity studies at five times the recommended intramuscular dose for 3 times the recommended duration of therapy resulted in no signs of toxicity. Administration: An initial 7-dose series is recommended: 250 mg intramuscularly every 4 days for 7 injections. ------------------------------------------------------------------------ -------- ------------------------------------------------------------------------ -------- Sodium hyaluronate (hyaluronic acid—HA) products have been used successfully for years to treat joint disease in several species including the horse. HA is a normal component of joint fluid and cartilage and serves many functions, one of which is to "lubricate" the soft tissue structures of the joint and decrease inflammation. Until recently, HA products were given only as intra-articular injections, directly into the joint space. Now there is an HA preparation that can be given intramuscularly (I.M.) and has shown beneficial results. Although the mechanism of action of HA is not entirely understood, it is recognized that sodium hyaluronate decreases synovial fluid inflammatory mediators (destructive enzymes) which may have a degradative effect upon articular cartilage. In addition to the anti-inflammatory actions, HA acts as a lubricating substance within the joint and provides a "protective barrier" over the synovial membrane. Sodium Hyaluronate is the joint disease therapy that helps stop acute damage before it becomes chronic. Sodium Hyaluronate (hyaluronic acid), is the same polysaccharide present in normal joint fluid to protect and lubricate joint cartilage and soft tissues. Sodium Hyaluronate is produced by a biofermentation process, resulting in such purity that it can be given intramuscularly for immediate bioavailability. A Colorado State University study* demonstrated systemic administration of Sodium Hyaluronate significantly decreased the synovial fluid concentrations of prostaglandins, glycosaminoglycan (GAG), and total protein that are associated with inflammatory joint disease in the horse. The systemic administration of Sodium Hyaluronate also decreased the severity of cellular infiltration and vascularity in the synovial membrane (i.e., decreased inflammation at the synovial membrane level). This study demonstrates that systemic administration of Sodium Hyaluronate decreases inflammation, products associated with inflammation, and the degree of lameness in horses with arthritis (joint inflammation). Administration: A series of 4 weekly intramuscular injections consisting of 20mg of Sodium Hyaluronate is recommended

another chmeically simaliae product is Sodium Pentosan Polysulphate (pps) but it is only avaible overseas atthis time. all these products rather than simply covering up pain, directly stimulates joint healing and repair. Anti-inflammatories, corticosteroids and NSAID's all relieve the symptoms of osteoarthritis but DO NOT ALTER THE DISEASE PROCESS. Both hydrocortisone and NSAID's have a marked inhibitory effect on the biosynthesis of the components of the extracellular matrix of cartilage which limits the early healing response of cartilage to injury. Jim

like i said b4 i'd suggest injecting into the muscle in the closest vicinity of the joint that's bothering you. it gets inject intramuscularly just like aas.

Found:biglaugh:

MORE INFO....MORE RESULTS....PLEASE!!!

Mule have you used the Sodium HA with Adequan at the same time?

So would this only be for arthritus, joint pain type relief. Or could people with injuries or just inflamation benefit from this. Ive got inflation, pain, and swelling around the end of my collar bone where a bone in my shoulder is basically almost rubbing against it(these bones are just closer together than normal). The doc said the only way to fix is to take off some of the end of my collar bone. Could this stuff benefit me?

i dunno, i'm no doctor bro, try asking him

Originally posted by Durabolin Mule have you used the Sodium HA with Adequan at the same time? no i haven't , just because of cost, i have used both quite a bit but never together, but if you satck them you will get great results, its a bit of overkill but the rsults would be good

since im completely new to injections, i dont know what kind of needle would be necessary, and how I would inject it. also where does the vial have to be stored?

since im completely new to injections, i dont know what kind of needle would be necessary, and how I would inject it. also where does the vial have to be stored? I'd imagine a 25ga 1" would be plenty to get wherever you needed it as long as you're not obese. As far as the vial storage. Look up the manufacturers website. Should have all the info there.

I just ordered 2 vials of the IM Equine version. My knees and elbows gould REALLY use this. I'll start injects as soon as I get the stuff in and will post results. Should be about 28 days total from what I'm reading. I think I'll be splitting up the injects into 4. One in each quad for knees and 1 in each tri for elbows. Maybe even forearms as that's where some of the pain radiates. We shall see.

hey guys i just ordered from entirelypets.com, and theyre asking for a prescription, and i dont think i can get one, what should i do..i really really wanted to use this. hey ripdtoshredz where did u get yours from?

my question is....I wrestle still and I know that when my ears get worn a little they will get cauliflower....so will taking this cause the same....will it cause abnormal cartilage growth in places other than your joints?