Albuterol and blood...
 
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Albuterol and blood lipids

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jboldman
(@jboldman)
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One of the side effects that most bbrs live with is elelvated blood lipids and depressed hdl cholesterol. Here is a novel effect of salbuterol(Albuterol). 16mg ( 8mg bid) reduced total cholesterol, ldl cholesterol and INCREASED hdl cholesterol. this is very interesting.

jb
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Effects of oral Albuterol on serum lipids and carbohydrate metabolism in healthy men.Maki KC, Skorodin MS, Jessen JH, Laghi F.
Edward Hines, Jr, Veterans Affairs Hospital, Hines, IL, USA.

beta(2)-Selective adrenergic agonists are used in the management of bronchial asthma and preterm labor. Due to their ability to increase muscle strength and size in animal models, new applications for these agents are also being explored for neuromuscular disorders and in rehabilitation. However, the effects of long-term beta(2)-agonist administration on lipoprotein and carbohydrate metabolism are incompletely understood. This investigation evaluated the effects of a beta(2)-agonist, Albuterol, on serum lipids and carbohydrate homeostasis in eight healthy nonsmoking men aged 24 to 61 years. Collection of fasting blood samples was completed in duplicate on separate days at baseline, during 14 days of oral Albuterol administration (Proventil Repetabs, 8 mg twice daily; Schering Pharmaceuticals, Kenilworth, NJ) and during a 7-day washout period. Carbohydrate homeostasis was evaluated using the minimal model technique at the end of the baseline and Albuterol periods. Fasting glucose and insulin, intravenous glucose tolerance, acute insulin response to intravenous glucose (AIRg), insulin sensitivity (Si), and glucose effectiveness (Sg) were not significantly changed during Albuterol administration. Significant alterations (P < or = .02) were observed in total cholesterol ([TC] -9.1% +/- 2.5%), low-density lipoprotein cholesterol ([LDL-C] -15.0% +/- 2.9%), and high-density lipoprotein cholesterol ([HDL-C] +10.4% +/- 3.2%) concentrations, as well as the TC/HDL-C (-17.4% +/- 2.6%) and LDL-C/HDL-C (-22.9% +/- 2.4%) ratios. During washout, TC and LDL-C returned to baseline levels, whereas HDL-C remained elevated by 5.8% +/- 2.4% (P < .05). Thus, Albuterol administration was associated with favorable changes in the serum lipid profile without marked impairment of glucose tolerance or its physiologic determinants.


   
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guijr
(@guijr)
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Great.

"The medals don't mean anything and the glory doesn't last. It's all about your happiness. The rewards are going to come, but my happiness is just loving the sport and having fun performing" ~ Jackie Joyner Kersee.


   
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oswaldosalcedo
(@oswaldosalcedo)
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Joined: 6 years ago
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nice find !

dr frankenstein


   
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razg
 razg
(@razg)
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Joined: 6 years ago
Posts: 24
 

Very interesting. It's also intriguing to see that they are using an effective cutting dosage.


   
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guijr
(@guijr)
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Joined: 7 years ago
Posts: 801
 

Maybe I'll try it again soon with a low dose this time in order to avoid lethargy and headache.

"The medals don't mean anything and the glory doesn't last. It's all about your happiness. The rewards are going to come, but my happiness is just loving the sport and having fun performing" ~ Jackie Joyner Kersee.


   
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liftsiron
(@liftsiron)
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Posts: 507
 

Very good find.

liftsiron is a fictional character and should be taken as such.


   
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Badlands
(@badlands)
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Joined: 6 years ago
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How does the 8mg twice a day translate into bodybuilding uses? Is that a low dose, usual dose or high dose?


   
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RaetherEnt
(@raetherent)
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Joined: 6 years ago
Posts: 76
 

I definately wouldn't start out with 8mg bid right away. I would recommend starting smaller and working up. That was my personal experience anyway. Others may be different.


   
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