Expired Anadrol

My pharmacist has told me in the past that you're definitely good to go with using them and they'll still have the same potentcy. He mentioned that depending on which product it is potency really doesn't start becoming a question till after a year or more after expiration.

what he said

x3

Thank you all my friends.

indeed, if they expired this year, i'd bet they are still 99% as potent. i'm currently using Nolvadex that expired 5 years ago i'd be a fool to think that the tabs are still worth 20 mg, but its good enough for on cycle estrogen management

I've used oils that expired longer than that before use (over 1 year) and still got great results.

I agree with BigCat. There's absolutely no reason to believe that the product might turn toxic, even years after its expiration date. Few cases are known where the active compound reacted with the binders to produce a toxic product, being degraded tetracycline the only one I am aware of. People often extrapolate the concept of expiration date applied to foods to medications, but they are two entire different scenarios. With foods, expiration dates are often used with the meaning of "past this point in time, bacterial growth might begin to reach unacceptable and dangerous levels". Yet this is not the case with medications at all, since there can be no bacterial growth to begin with, given the null water activity. Therefore the dangers of expired foods do not apply to expired drugs, since the meaning of "expired" is entirely different: "we do not guarantee that past this date this product is going to contain over 90% of active compound". The issue of a degradation product that happens to be highly toxic is probably very unlikely.

As far as potency goes it depends on the substance: Regenthal et al showed in a report that theophylline retained 90% of potency for about 30 years.

The pharmacologic stability of 35-year old theophylline
R Regenthal

The propensity to preserve and to hoard drugs over the years at home is a well-known phenomenon and offers the possibility for intentional and accidental drug poisoning in man. We report a case of acute theophylline poisoning in an 80-year old women after ingestion of ‘Asthmo-Kranit1 ’, a 35-year old combined preparation containing theophylline and aminopyrine as the main ingredients. The patient developed the typical clinical picture of a symptomatic theophylline poisoning with flush, tremor, tachycardia, hyperventilation, hypotonia, and hyperglycaemia. The clinical course after treatment with beta-blockers was without complications. The determination of theophylline in tablets showed stability of 90% of the labelled amount of the drug 30 years beyond the expiration date. The case illustrates the prolonged shelf stability and pharmacological potency of some pharmaceuticals and points to the risk of longoutdated prescriptions. Physicians should primarily not underestimate drug toxicity in consequence of old-age pharmaceuticals.

Key Words: Asthmo-KranitR • poisoning • shelf stability • theophylline

Human & Experimental Toxicology, Vol. 21, No. 6, 343-346 (2002)
DOI: 10.1191/0960327102ht262oa

Posted by: Bilter

I've used oils that expired longer than that before use (over 1 year) and still got great results.

Me too. As long as the oils are in a sterile environment, you're good.