Boldenone, any feed back Pro or con?

Has anyone had any feed back on this supplement? Seems to be well referenced: Reduced Androgenic Activity boldenone is classified as an anabolic steroid, exhibiting much less androgenic activity than its analogue testosterone. This is because unlike testosterone, boldenone is a poor substrate for the 5-alpha reductase enzyme [8] . This is the enzyme responsible for converting Testosterone to the more potent steroid dihydrotestosterone in many androgen responsive tissues such as the skin, scalp, prostate and central nervous system. Consequently the local potency of testosterone is increased significantly in these tissues, often allowing it to trigger unwanted side effects such as oily skin, acne, body/facial hair growth and male pattern hair loss (for those with a genetic predisposition). But boldenone tends to interact with the 5-beta reductase enzyme instead, which reduces this steroid into a very weak binder of the androgen receptor instead of potentiating its activity. Consequently boldenone is much milder in terms of androgenic side effects compared to testosterone, being much more similar to nandrolone in this regard. A Naturally Occurring Hormone In order for any prohormone to be classified as a nutritional supplement, the compound in question must be “naturally occurring”. This means that we must isolate a clear source for it in nature, without human synthesis. Thankfully 1,4-androstadienedione was shown unquestionably to be a natural androgen in cows. The first study to isolate this compound was conducted back in 1956, where scientists believed that it was most likely produced from progesterone in the animal’s gastrointestinal tract [9] . Later studies show the production of this hormone in cow ovarian tissues however [10] , suggesting another location and method of endogenous production. We can also look toward studies in the agricultural industry, where the natural occurrence of 1,4-dienones [11] have caused some difficulty and debate over the screening processes used for detecting the illegal use of boldenone in cattle. Many have suggested threshold limits to prevent false positives due to the low level of 1,4-diene androgens that may be present naturally in these animals. Nutrition Facts Serving Size: 1 capsule Servings Per Container: 60 Amount Amount per Serving: 14-androstadiene-3 17-dione 100 mg Other Ingredients: Magnesium stearate, maltodextrin. Recommended Use: Take 1-2 capsules 2-3 times daily. Do not exceed 12 weeks of continuous use. Warning: This product contains ingredients that may cause acne, body/facial hair growth, mood changes, male pattern hair loss, breast enlargement, increased heart disease risk, testicle shrinkage, and infertility in males. Women should be especially careful with the use of male steroid hormone precursors, as they can potentially cause virilizing side effects such as increased facial and body hair, voice deepening and clitoral enlargement. Higher doses may increase these risks. If you are pregnant, at risk for or suffering from prostate disease, heart disease, high blood pressure or breast cancer you should not use this product. As with all dietary supplements consult a physician or medical authority before using. References: [1] Metabolism of 1-dehydroandrostanes in man. I. Metabolism of 17-beta-hydroxyandrosta-1,4-dien-3-one, 17-beta-cyclopent-1-enyloxyandrosta-1,4-dien-3-one (quinbolone) and androsta-1,4-dien-3-one (1). Galletti F and Gardi R. Steroids 18 (1971) 39-50. [2] Metabolism of 1-dehydroandrostanes in man. III. Metabolism of 17-beta-hydroxy-5a-androst-1-en-3-one, 17-beta-(1-methoxy-cyclohexyloxy)-5-a-androst-1-en-3-one (mesabolone) and 5a-androst-1-en-3,17-dione. Galletti F and Gardi R. J Steroid Biochem 3 (1972) 933-6. [3] Biosynthesis of Estrogens, Gual C, Morato T, Hayano M, Gut M and Dorfman R. Endocrinology 71 (1962) 920-25 [4] Aromatization of androgens to estrogens mediates increased activity of glucose 6-phosphate dehydrogenase in rat levator ani muscle. Endocrinol 106(2):440-43 1980 [5] The pentose phosphate pathway in regenerating skeletal muscle. Biochem J 170: 17 1978 [6] Activation of the somatotropic axis by testosterone in adult males: Evidence for the role of aromatization. Weissberger and Ho. J Clin Endocrinol Metab 76 (1993) 1407-12. [7]Modulation of the cytosolic androgen receptor in striated muscle by sex steroids. Rance, Max. Endocrinol 115 (1984) 862-6 [8] Metabolism of Beldenone in Man: gas Chromatographic/Mass Spectrometric Identification of Urinary Excreted Metabolites and Determination of Excretion Rates. Schanzer, Donike. Bol Mass Spec. 21 (1992) 3-16 [9] Identification of C19 Steroids in Bovine Feces. Miller, W.R., C.W. Turner, D.K. Fukushima and I.I. Salamon: J. Biol. Chem. 1956 220: 221 [10] The in-vitro metabolism of progesterone-c14 to Delta-1,4-Androstadiene-3,17-dione by a cystic bovine ovary. Gawienowski A. M., Lee S.L. and Marion G.B.: Endocrinology 69 (1961) 388-90. [11] C. J. M. Arts, R. Schilt, M. Schreurs and L.a. Van Ginkel, in Proceedings of the Euroresidue III Conference, Veldenhoven, 6-8 May 1996 ed. N. Haagsma and A. Ruiter, University of Utrecht, Utrecht, The Netherlands, 1996, p. 212