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04/07/2019 1:15 pm
Good! Plus maybe Prolactin, LH, FSH, DHT, Total Test.
sure!
dr frankenstein
Topic starter 04/07/2019 1:34 pm
Just curious, but what are your test levels, off cycle and on cycle?
"The medals don't mean anything and the glory doesn't last. It's all about your happiness. The rewards are going to come, but my happiness is just loving the sport and having fun performing" ~ Jackie Joyner Kersee.
04/07/2019 1:51 pm
Just curious, but what are your test levels, off cycle and on cycle?
have to take,but I already imagine them.........
...........lol............
maybe rebound,like cortisol levels.
God willing ..................lol..........
pd:creatinine,bun,sodium.
dr frankenstein
Topic starter 04/07/2019 2:18 pm
? .
"The medals don't mean anything and the glory doesn't last. It's all about your happiness. The rewards are going to come, but my happiness is just loving the sport and having fun performing" ~ Jackie Joyner Kersee.
04/07/2019 2:46 pm
so just for curiosity, what are your alt and ast?
jb
04/07/2019 3:03 pm
so just for curiosity, what are your alt and ast?jb
around 50-60 U/L.
I have a good liver.
it is like my estradiol levels, ever low on test,boldelone,Dbol.
8 pg/ml (under normal lower limit!).
but cortisol..............................post cycle..............well (but
Pharmacol Rep. 2005 Nov-Dec;57(6):766-73. Related Articles, Links
Effects of some new antidepressant drugs on the glucocorticoid receptor-mediated gene transcription in fibroblast cells.
Augustyn M, Otczyk M, Budziszewska B, Jagla G, Nowak W, Basta-Kaim A, Jaworska-Feil L, Kubera M, Tetich M, Leskiewicz M, Lason W.
Laboratory of Immunoendocrinology, Department of Experimental Neuroendocrinology, Institute of Pharmacology, Polish Academy of Sciences, Smetna 12, PL 31-343 Krakow, Poland.
Antidepressant drugs are thought to counteract effects of hypercortisolemia, frequently associated with depression, by lowering cortisol level and by modifying the function of glucocorticoid receptors (GR). Indeed, classical antidepressants inhibit corticosteroid-induced gene transcription in cell cultures. The aim of the present study was to investigate effects of new generation antidepressant drugs on GR function in mouse fibroblast cells (L929), stably transfected with mouse mammary tumor virus-chloramphenicol acetyltransferase (MMTV-CAT) plasmid (LMCAT cells). It has been found that reboxetine (at 10 and 30 microM), venlafaxine, citalopram and mirtazapine (at 30 microM), but not milnacipran, in statistically significant manner inhibited corticosterone-induced gene transcription. However, the effects of new generation antidepressant drugs were weaker than those evoked by imipramine, which was active already at 3 microM concentration. Further studies on the mechanism of antidepressant action on GR function revealed that protein kinase C, but not mitogen-activated protein kinases (MAPK), glycogen synthase kinase (GSK-3) and protein kinase B (PKB, Akt) play a role in this phenomenon.
or
Effect of the antiglucocorticoid RU38486 on protein metabolism in unweighted soleus muscle.
Tischler ME.
Department of Biochemistry, University of Arizona Health Sciences Center, Tucson.
Unweighting the hindlimbs by tail Suspension of juvenile rats leads to atrophy of the soleus muscle, especially during the third day of unweighting. Although a previous study using adrenalectomized animals suggested a minimal role of glucocorticoids in this atrophy, the inability of adrenalectomized animals to release other adrenal hormones could have been important. Therefore, the influence of oral administration of RU38486 [11-beta-(4-dimethylaminophenyl) 17-beta-hydroxy 17-alpha(prop-1-ynyl) estra 4,9-dien 3-one], a selective glucocorticoid antagonist, on protein metabolism in the unweighted soleus was studied. The effectiveness of RU38486 treatment was demonstrated in hindlimb-suspended rats as the drug abolished the increase in soleus glutamine synthetase activity shown previously to be caused by elevated circulating glucocorticoids. The slower weight gain of suspended rats was unaffected by the drug. After 3 days of unweighting, the difference in protein content from weighted soleus muscle was not diminished significantly by RU38486 (-25%, vehicle only; -18%, RU38486-treated). However, in both weight-bearing and suspended animals, RU38486 seemed to promote protein accretion between days 2 and 3 of the experiment; ie, unweighted muscle seemed to lose less protein. All suspended animals showed slower (-58% to -64%) fractional in vivo rates of synthesis. RU38486 did not affect these percent differences in fractional protein synthesis after either 2 or 3 days of unweighting. The apparent improvement in protein balance likely resulted from a decline in protein degradation in both the weight-bearing (-26%) and unweighted (-35%) soleus.
my hypothyroidism and hypoadrenalism, i already controlled them (with fast roids,only on workouts day and take them at morning).
dr frankenstein
Topic starter 04/07/2019 3:27 pm
Do you use meds and/or supplements to protect your liver? If so, which ones?
"The medals don't mean anything and the glory doesn't last. It's all about your happiness. The rewards are going to come, but my happiness is just loving the sport and having fun performing" ~ Jackie Joyner Kersee.
04/07/2019 3:53 pm
Do you use meds and/or supplements to protect your liver? If so, which ones?
silimaryn (legalon) and tons of water.
dr frankenstein
Topic starter 04/07/2019 4:16 pm
This med is sold in my country, are you from Brazil? And how much do you take?
"The medals don't mean anything and the glory doesn't last. It's all about your happiness. The rewards are going to come, but my happiness is just loving the sport and having fun performing" ~ Jackie Joyner Kersee.
04/07/2019 4:39 pm
silymarin aka milk thistle extract, commonly available everywhere.
jb
04/07/2019 5:02 pm
This med is sold in my country, are you from Brazil? And how much do you take?
from venezuela.
silymarin aka milk thistle extract, commonly available everywhere.
correct.
dr frankenstein
04/07/2019 5:04 pm
Abdominal ultrasound. Hmmmmm
I wonder how much that would cost me? I wonder if I could a Doc on board with that.
Topic starter 04/07/2019 5:30 pm
Say to your Doc. that you've been having severe stomach aches after a box punch, karate kick or something, sorry for the cheating thing .
"The medals don't mean anything and the glory doesn't last. It's all about your happiness. The rewards are going to come, but my happiness is just loving the sport and having fun performing" ~ Jackie Joyner Kersee.
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