6 Bromodione

sounds like it is a made up compund used in an otc supplement. I get suspicious when google and medline come up with no hits. at this point i would not wast my money

jb

6-bromodione (the long name is 6 bromoandrostenedione) is an aromatase inhibitor.
I saw pubmed and this compund is effective in the aromatase inhibition but It has not much scientific researches.
For this reason I would know your opinions and experiences.
Regards, crack.

1: Steroids. 1980 May;35(5):533-41. Links

Inhibition of estrogen synthesis in human breast tumors by testololactone and bromoandrostenedione.Budnick RM, Dao TL.
The inhibition of aromatase enzyme in human breast tumors by delta 1-testololactone, testololactone, 6 alpha-bromoandrostenedione, and 6 beta-bromoandrostenedione was investigated. Estrone and estradiol synthesis from androstenedione was reduced in 3 tumor incubations by the presence of 0.13 mM delta 1-testololactone and testololactone. 6 alpha- and 6 beta-bromoandrostenedione (2.0 microM) were also shown to block estrogen synthesis in 2 tumors. Furthermore, Lineweaver-Burk plots revealed that all 4 compounds are competitive inhibitors of androstenedione aromatization. An apparent Km of the aromatase enzyme for androstenedione of 0.08 microM and a Vmax of 23 pmol of estrone synthesized/g tumor/hr were determined for one human breast tumor specimen. These results demonstrate that these aromatase inhibitors may be useful for the treatment of breast cancer.

it still sounds like an obscure compound that someone dug up to add to an otc supplement to spin it. with so little research available, if your interest is in an AI, why not stick to a proven tried and true one that you know works and in what doses it works.

jb