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Topic starter
22/01/2020 12:27 am
I usually do it sub q but have read it is more bioavailable im. so i im a better way then?
power is nothing without control
22/01/2020 12:52 am
I have heard IV is even better....not sure my self. I was doing it IM post workout 3x per week
24/01/2020 8:50 am
i believe that im leads to higher plasma levels faster but at the end of the day, there is no difference in the bioequivalence of either so it is really a matter of preference. i do it SQ to give my muscles a break from injections.
jb
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PREGNYL®
RA 2400 ZA S1 (ref 1.0).
SCHEDULING STATUS:
S4
PROPRIETARY NAME
(and dosage form):
PREGNYL®
Pregnyl® 1 500 IU powder for solution for injection, provided with Solvent for Pregnyl
Pregnyl® 5 000 IU powder for solution for injection, provided with Solvent for Pregnyl
COMPOSITION
PREGNYL contains 1 500 and 5 000 I.U. Chorionic Gonadotrophin per ampoule
Each 1 mL ampoule of Solvent for Pregnyl contains 0,9% m/v sodium chloride in water for injection
PHARMACOLOGICAL CLASSIFICATION
A/21.10/Trophic hormones
PHARMACOLOGICAL ACTION
Pharmacodynamics
Pregnyl contains human Chorionic Gonadotrophin (HCG) which has luteotrophic (LH) activity.
In the female Pregnyl substitutes the endogenous mid-cycle LH surge to induce the final phase of follicular maturation, leading to ovulation.
In the male Pregnyl stimulates Leydig cells to promote the production of testosterone.
Pharmacokinetics
Maximal plasma hCG levels will be reached in males approximately 6 and 16 hours after a single intramuscular or subcutaneous injection of hCG, respectively and in females after approximately 20 hours. HCG is approximately 80 per cent metabolized, predominantly in the kidneys. Intramuscular and subcutaneous administration of hCG were found to be bioequivalent regarding the extent of absorption and the apparent elimination half-lives of approximately 33 hours. On basis of the recommended dose regimens and elimination half-life, cumulation is not expected to occur.