Big Cat
Big Cat
@big-cat
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Joined: Jun 23, 2018
Last seen: May 25, 2020
Topics: 11 / Replies: 334
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RE: The designer drug connection

Was it the article in the San Jose Mercury news by Almond and Webbe ? I read that one too. They do make a very convincing case. Although I do not want...

7 years ago
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RE: Warning About Topical Spironolactone!!

that's the curious part, both finasteride and spiro should increase test levels, or keep them the same, since the test is not bound to the AR.

7 years ago
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RE: Warning About Topical Spironolactone!!

That's what I was told too. But it doesn't seem to match the chemical properties of the drug and it doesn't appear to be the case at least for hitmeba...

7 years ago
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RE: Warning About Topical Spironolactone!!

Nizoral contains ketoconazole, an anti-mycotic agent. Its known to lower androgenic effects by inhibiting steroidogenisis, not by blocking the androge...

7 years ago
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RE: Warning About Topical Spironolactone!!

Actually that would have been my guess too, Spironolactone is a fairly lipophillic drug, and the normal ways in which it is applied topically would on...

7 years ago
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RE: THG what is it?

Posted by: JGUNS Maybe I missed it but so what is the half life? It degrades very quickly I understand.The thing I find most striking about it is tha...

7 years ago
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RE: Lets start a discussion on neural effects of steroids

There are a number of NMDA blockers like Dizocilpine. But I generally don't try to mess with that purposefully.

7 years ago
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RE: Lets start a discussion on neural effects of steroids

Technically its not sans cortisol but with moins cortisol, so yes, definitely.

7 years ago
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RE: Lets start a discussion on neural effects of steroids

Good point, factor in that testosterone antagonizes those GR's and you may be on to something.

7 years ago
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RE: Lets start a discussion on neural effects of steroids

Posted by: prolangtum I dont feel like going on a pubmed search tonight, heres some random ramblings. No need to stress yourself, we are all old and ...

7 years ago
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RE: Lets start a discussion on neural effects of steroids

Re: I have a load of interest in this field Posted by: BeLargeMini Just happens to be what I am thinking about including for my studies as a grad(whe...

7 years ago
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RE: Lets start a discussion on neural effects of steroids

One thing i did find interesting is that part where in contrast to neuroactive steroids, AAS had negative modulation. THese neuroactive steroids inclu...

7 years ago
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