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Diet and Nutrition
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Topic starter
29/03/2020 2:35 pm
Anyone ever tried this drug. I heard it had some pretty nasty sides like depression and what not. Here is a little splat on it.
Acomplia represents one of the latest and indeed a most novel method for controlling body weight. Acomplia operates by being a cannabinoid receptor antagonist. This means that Acomplia prevents the normal action of endogenous cannabinoid in the brain from stimulating the so-called CB1 receptors. It would appear that these receptors stimulate appetite and therefore when they are “subdued” so is the need to eat.
The clinical trials that have been run over the past few years are impressive and have shown that these receptor sites may be responsible for more than just appetite, because the results show that Acomplia also aids people to stop smoking and even improves cardiovascular factors such as cholesterol ratios.
With specific regard to weight loss, the human trials have shown an average weight loss of 10% of bodyweight, most importantly that weight has remained off even up to 2-years later. Also importantly, it would appear that the majority of weight is actually lost from the difficult to lose area around the waist. The average figures from the trials show a loss of fat of 20 lbs (9 Kg) and 3 inches (8 cm) diameter taken off the waist.
Additional trials have been undertaken to help smokers kick the habit. Even here Acomplia has been successful, showing that persons using Acomplia have double the chance of quitting smoking for good, and perhaps importantly also helping those smokers from not gaining any weight once they stop smoking, (as it is often the case that smokers trying to quit substitute their cigarettes with food etc.).
On top of that, Acomplia has also been shown to improve HDL (good cholesterol) and triglyceride levels, showing benefit for diabetes and heart conditions.
Meanwhile, Acomplia has shown few and minor side effects in the clinical trials, some of which have been conducted continuously for 2-years. Side effects noted in the studies were mainly mild and transient consisting (in order of frequency) of nausea, dizziness, diarrhoea, vomiting, hypoglycaemia and anxiety.
The most beneficial doses noted in the trials have been 20 mg. daily.
Perhaps it is no wonder that Acomplia is expected to be a blockbuster drug now it is available in Europe.
i was the 1997 International Spelling Bee Winnur
29/03/2020 3:03 pm
I would not want to be among the first to use this drug. It works by cutting off appetitive drive. How many of those drives? There may be a good potential to induce depression and anxiety with this drug. Wait till it's been around a while.
And we'll collect the moments one by one. I guess that's how the future's done. Feist, "Mushaboom", 2005
29/03/2020 3:23 pm
i agree. note that it is not recommended for patients who are on anti-depressants since it can increase the chance of suicide in that population.
jb
Topic starter
29/03/2020 3:40 pm
They were touting it as a mircale drug on the IAS website. I had forgotten about it and looked at the site the other night. IAS was showcasing the drug as having few to no real sides.
i was the 1997 International Spelling Bee Winnur
29/03/2020 4:02 pm
sounds promising.
Topic starter
29/03/2020 4:18 pm
Note: I think my mom is taking it to quit smoking and she seems to be a bit "off" lately. I think she is getting some of the depression sides from it. Like head doc or someone else said Accomplia is designed to kill your drive(s) for food and smokes. I guess the real question is what other drives is it killing
i was the 1997 International Spelling Bee Winnur
29/03/2020 4:36 pm
A lot of times companies that state that very little sides occur, are not telling the full truth or the sides are minor but still impacts your everyday life in some way.
29/03/2020 5:01 pm
True and depression is not a minor side.
Seabiscuit Hogg is a fictious internet character. It is not recommended that you receive medical advice from fictious internet characters.
SBH :)
Topic starter
29/03/2020 5:30 pm
True and depression is not a minor side.
Truer words have never been spoken
i was the 1997 International Spelling Bee Winnur
29/03/2020 6:00 pm
It depends how bad the depression is. A very slight negative feeling, but a great improvement over whatever it was prescribed for is sometimes worth it. Although any type of depression is not what I'm really looking for. I'd say getting off steroids can sometimes have that effect on people but people still do it.
Topic starter
29/03/2020 6:31 pm
Thats why I never get off(j/j) Its not the steroids that causes depression its the lack of androgens that causes it... In essence the lack of steroids
i was the 1997 International Spelling Bee Winnur
29/03/2020 6:50 pm
i agree. note that it is not recommended for patients who are on anti-depressants since it can increase the chance of suicide in that population.jb
Many of the studies that show depression when using this drug, were studies done with alcoholics and drug addicts, where the drugs and alcohol were replaced with Acomplia. I question was it the Acomplia that caused the depression or the removal of the drugs and alcohol.
Acomplia is a cannabinoid receptor antagonist which seems to be a very effect anti craving agent. Because cannabinoid receptor activation reduces learning, reduces memory formation, as well as enhances food intake, other uses of acomplia might include enhancement of learning and memory as in early stages of dementia.
I have used acomplia a number of times w/o any sign of depression.
liftsiron is a fictional character and should be taken as such.
Topic starter
29/03/2020 7:10 pm
well said. So, how would you rate it and what would/did you use it for
i was the 1997 International Spelling Bee Winnur
29/03/2020 7:30 pm
I would rate it fair to good. I used it to stop cravings on a cutting diet for BB competition. It without doubt cut cravings for carbs without killing my appetite for required foods. Rimonabant is the name more commonly used on BB boards.
liftsiron is a fictional character and should be taken as such.
Topic starter
29/03/2020 7:58 pm
Kewl deal. It sounds very promosing
i was the 1997 International Spelling Bee Winnur