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Topic starter
26/04/2019 5:20 am
as if there were not already enough reasons:
jb
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Nicotine Inhibits Pulsatile Luteinizing Hormone Secretion in Human Males But Not in Human Females, and Tolerance to This Nicotine Effect Is Lost within One Week of Quitting Smoking
Toshiya Funabashi, Akane Sano, Dai Mitsushima and Fukuko Kimura
Department of Neuroendocrinology (T.F., A.K., D.M., F.K.), Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan; and International University of Health and Welfare (F.K.), Tokyo 107-0062, Japan
Address all correspondence and requests for reprints to: Fukuko Kimura, M.D., Ph.D., Department of Neuroendocrinology, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawaku, Yokohama 236-0004, Japan. E-mail: [email protected].
Context and Objective: Despite having increased knowledge of the adverse reproductive effects of smoking, it is unclear whether nicotine affects the pulsatile LH secretion in humans. We addressed this issue in male and female smokers and nonsmokers.
Subjects and Methods: Twenty-nine male and 16 female nonsmokers and smokers were recruited as volunteers. In male smokers, nicotine effect was also studied before and after quitting smoking. In females, cyclic ovulatory function was assessed by measuring basal body temperature, and sampling studies were performed during the follicular phase. In the morning of the sampling day, an iv catheter was inserted into an anterobrachial vein, and blood samples (1.0–1.5 ml each) were taken at 10-min intervals for 480 min, during which, at 240 min, nicotine was administered via a transdermal patch (Nicotinell transdermal therapeutic system) containing 17.5 mg nicotine. Plasma LH was measured by immunoradiometric assay kits.
Results: Nicotine significantly lengthened the interpulse interval of pulsatile LH secretion in male nonsmokers but not in female nonsmokers. In male smokers, nicotine did not lengthen the interpulse interval, and in female smokers it was also ineffective. After quitting cigarette smoking in male smokers, the refractory to nicotine effect disappeared within 1 wk.
Conclusions: We conclude that nicotine inhibits pulsatile LH secretion only in males, and the tolerance developed to the nicotine effect disappears within 1 wk of quitting cigarette smoking. However, we cannot deny the possibility that nicotine effect would have been detected in females if more subjects had been studied.
26/04/2019 5:53 am
i'm addicted to menthol... if i try the patch i will have to lather up in sportscreme and then use the patch.
Disclaimer:
saint808 is presenting fictitious opinions and does in no way, shape or form encourage, use nor condone the use of any illegal substances or the use of legal substances in an illegal manner. The information discussed is strictly for entertainment purposes only and shall not take the place of qualified medical advice.
To quote Oscar Wilde, "They say we destroy the things we love, but really the things we love destroy us."
It's strange, how laughter looks like crying, with no sound and rain drops taste like tears, without the pain.
26/04/2019 9:39 am
smoking is a stupid thing to do, period.
26/04/2019 10:39 am
Oh the memories...
The great smoke debate of 03....
Nandi in one corner...everyone in the other...
If only we had this info then.
26/04/2019 11:21 am
The great smoke debate of 03....
Nandi in one corner...everyone in the other...
LOL! that was a fun match to watch...
"In any contest between power and patience, bet on patience."
~W.B. Prescott
"Only two things are infinite, the universe and human stupidity, and I'm not sure about the former."
~Albert Einstein
Topic starter
26/04/2019 12:12 pm
jb
26/04/2019 1:05 pm
Smoking Why would anyone?
liftsiron is a fictional character and should be taken as such.
26/04/2019 1:42 pm
Smoking Why would anyone?
to prevent ulcerative colitis
26/04/2019 2:27 pm
to prevent ulcerative colitis
The risks from cigarettes far outweigh the potential benefits of their nicotine.
liftsiron is a fictional character and should be taken as such.
Topic starter
26/04/2019 3:02 pm
i feel it heating up!
jb
26/04/2019 4:01 pm
well .i have lost dear family loved ones both from smoking and non smoking...personaly i think if you want to smoke ..go for it ..if you dont ..then dont ...there is nobody out there who says to me "oh you shouldnt do bodybuilding" its my choice...
but i must agree with liftsiron "why would anyone smoke "
it is not good and doesnt help with the weight training either..
but its everyones own choice rite !!!
MASTERCHEF::LECTURER::TEACHER:: AND MOST IMPORTANT F/T DAD
26/04/2019 4:34 pm
SAYS IT ALL REALLY
Smoking and Bodybuilding
By: Bryan Kenny
I was having a hard time thinking of a topic for this article, so I decided to check out the Teen Bodybuilding section of the message boards. And there it was, the perfect topic, smoking and bodybuilding, so I went and did a bit of research. To sum it up into a few short words YOU WON'T GET ANYWHERE! Pretty much everybody has friends that smoke and if you're like me then you really want them to quit, but there's not much you can do about it, because its an addiction and addictions are complicated, but I don't want to get into all the psychological crap, that's not what I want to talk about.
Smoking and bodybuilding just don't mix, for one thing the cardio part of your workout program will be screwed, and eventually you'll be so weak that the rest of your program will be just as screwed, and in result you're screwed. When you smoke you're body doesn't get the oxygen it needs, and then your blood won't get the oxygen it needs. Not to mention your teeth and fingers will be stained yellow, and you wont have much luck with the ladies. We've all heard of Carbon Monoxide, its in car exhaust, comes out of smoke stacks on factories, and its a by-product of tobacco, so just think of smoking as sucking on a rusty exhaust pipe, not a pretty picture eh?
Personally I find smoking disgusting, I try to get as many people to quit as I can, but so far I haven't been very successful, like I said it's an addiction. But at least I'm trying, that's gotta count for something right?
SO BASICLY SMOKING AND BODYBUILDING DON'T MIX! YOU GOTTA PICK ONE....TOUGH CHOICE RIGHT?
MASTERCHEF::LECTURER::TEACHER:: AND MOST IMPORTANT F/T DAD
29/04/2019 9:41 am
AND IF EVERYONE HERE HASNT GIVEN YOU ENOUGH REASONS WHY TO STOP (JUST THINK OF THE CHILDREN)
MASTERCHEF::LECTURER::TEACHER:: AND MOST IMPORTANT F/T DAD